Inqubo Yokukhiqiza Ukuhlelwa Kwemizila Kususelwa Ekugomeni Okucacile

Ngokuya ngokuhlaziywa kwesimo socwaningo, ekusetshenzisweni kwe-algorithm ehlakaniphile ekuhlelweni komzila wenqubo yezingxenye zegobolondo lomkhumbi-mkhathi, umphumela we-algorithm awumuhle ngenxa yenani elikhulu lezici zokucubungula. Ngama-algorithms ahlakaniphile, i-AIS ithembele kunqubo yayo yokwenza izinto ukufeza izinzuzo ezinkulu ngejubane lokuhlangana le-algorithm, kepha inokuphazamiseka kokuwela kalula kusixazululo sendawo esifanele, esivimbela kakhulu ukusebenza kwe-algorithm.

Mayelana nalokhu, lesi sahluko sithuthukisa i-algorithm yokuzivikela yokuzivikela ngokuhlaziya inqubo ethize yokuvikela amasosha omzimba, futhi siphakamisa indlela yokuhlela enobuhlakani yenqubo ngokususelwa ku-algorithm yomzimba ethile yokufakelwa (Artificial Specific Immune System, ASIS). I-algorithm ye-ASIS ilingisa ukugoma futhi isebenzisa i-Dijkstra algorithm ukukhiqiza ama-antibodies okuqala aphezulu. Ngalesi sizathu, i-antibody iyahlanganiswa futhi iguqulwe ngokusebenzisa i-algorithm yokuzivikela yokuzivikela ukuze ithole i-antibody efanelekile.

Imephu ethile yomqondo wokuzivikela wokuhlelwa kwemizila yenqubo

I-biological immune system iwuhlelo olusabalalisiwe noluzimele lokucubungula ulwazi, olukhombisa ukufana, ukusatshalaliswa, ukuzivumelanisa nezimo, ukuzihlela kanye nezinye izici, ngokuqashelwa okuqinile, amakhono okufunda kanye nenkumbulo. Lapho i-antigen itholwa amasosha omzimba, amangqamuzana aveza ama-antigen afana nama-macrophage agwinya futhi agaye i-antigen, futhi abonise izinqumo ze-antigenic phezulu, ezibonwa amangqamuzana omzimba njengamaseli B nama-T cell. 

Ngemva kokuqaphela i-antigen, amangqamuzana omzimba omzimba ahlangene futhi aguquke (okuthiwa ukwanda nokuhlukaniswa kwe-immunology), akhiqiza amasosha omzimba ahlukahlukene, abophe ku-antigen ukuze aqede i-antigen. Phakathi kwazo, ukuziphatha kwe-cloning nokuguqulwa kwamangqamuzana omzimba omzimba kulawulwa indlela yokulawula i-immune, kuhlanganise nezindlela ezimbili zokulawula, ukulawulwa okuhle kanye nokulawulwa okungalungile.

Kodwa-ke, empilweni yangempela, ngenxa ye-viral enamandla yezifo ezithile ezintsha, amasosha omzimba awakwazi ukuwaqeda ngokuphumelelayo ngesikhathi esifushane. Ngakho-ke, ukugoma okwenziwa kuvame ukusetshenziselwa ukuqondisa ukukhiqizwa kwama-antibody kanye nokusheshisa inqubo yokuzivikela komzimba. Phakathi kwazo, ukusetshenziswa kokugoma okwenziwa ukukhiqiza amasosha omzimba kubizwa ngokuthi ukuzivikela okuthile.

Ngokufanayo, ekuhleleni umzila wenqubo, inani lezici zokucubungula zezingxenye zegobolondo lemikhumbi-mkhathi likhulu, okubangela ukuthi i-algorithm yokuzivikela yokwenziwa iwele kalula kokuphezulu kwendawo, futhi umphumela wokugcina awuhlangabezani nezidingo zobunjiniyela. Ngakho-ke, lesi sihloko sidweba indlela ethile yokuzivikela komzimba, isungula imodeli ye-algorithm ye-ASIS, futhi yenza ukuhlelwa komzila wenqubo. Ngokuya ngencazelo yesigaba 2.2, imephu yomqondo yokuhlela umzila wenqubo ku-algorithm ye-ASIS inikezwa:

• (1) I-Antigen ibhekisa kumatrix esinyathelo esisebenzayo, futhi izichasiso ze-antigenic zibhekisa kumapharamitha ku-matrix yesinyathelo sokusebenza.
• (2) I-Antibody isho indlela yenqubo eyenziwe yi-ASIS.
• (3) Umuthi wokugoma ubhekisa kwi-Dijkstra algorithm. I-antibody esezingeni eliphakeme ekhiqizwe isenzo sokugoma ibhekisa kumzila wenqubo esezingeni eliphakeme owenziwe yi-Dijkstra algorithm.
• (4) Ukuhlangana nokuguqulwa kwesimo kusho ukuthi inqubo yenqubo inyuswa ngenombolo ngokuziphindaphinda, futhi izinyathelo zenqubo nokulandelana emzileni wenqubo kushintshaniswa ngezindlela ezithile zokulungisa.
• (5) Umthethonqubo omuhle nomthethonqubo ongemuhle Umthethonqubo omuhle ubhekisa kundlela yokulungisa ngokuya ngobumbano. 

Ubudlelwano buchaza ikhwalithi yomzila wenqubo. Ukuphakama kwekhwalithi yomzila wenqubo, kuphakama ubumbano; ukulungiswa okungekuhle kusho indlela yokulungisa ngokususelwa ekuvimbeleni. , Izinga lokuvimbela lilingana ngqo nokuhlushwa, futhi ukumiswa kubonisa inani lendlela efanayo yenqubo ngokuphelele. Ukukhula okukhulu kwesilinganiso, ukuphakama kokuhlushwa kuyanda. Ubudlelwano nokuvinjelwa ndawonye kunquma inani lamakhophi womzila wenqubo.

Xhumanisa nale ndatshana: Inqubo Yokukhiqiza Ukuhlelwa Kwemizila Kususelwa Ekugomeni Okucacile

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